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Edmund  Nelson's avatar

Is there a "Cardiovascular disease is a personal choice" version? I've been trying hard recently and got my LDL to below 80 but it's been stubborn to go significantly below that (my most recent test result was 75 but it's really been a lot slower since reaching 80)

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Dan Elton's avatar

I'm not an expert!! But, my general impression is that unless you're able to do an extreme regimine, like Bryan Johnson, diet and exercise interventions are not going to move the needle much. Probably I should have mentioned it, but it's pretty implicit in the piece.

But even Bryan Johnson takes red yeast rice, which is a natural statin, about as strong as prescription.

What types of things are you trying?

By the way, in addition to LDL-C you should be checking ApoB, Peter Attia says it's better -- ApOB sits on the outside of LDL and some other of the "bad" cholesterol particle types. You'll get a gauge of particle count, whereas LDL-C is the total amount in the particles.

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Ebenezer's avatar

"But even Bryan Johnson takes red yeast rice, which is a natural statin, about as strong as prescription."

So why do we need OTC statins in that case?

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Dan Elton's avatar

Good question RE red yeast rice extract! Well, unfortunately, the FDA has been cracking down on it and sets limits on how much of the active ingredient it can contain. Also, with such supplements, he never know exactly how much you’re getting.

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Edmund  Nelson's avatar

I actually at one point did a BJ style intervention where I tracked everything I ate for a good 6 months, it's what got me from 104 to 78. I'd eat Chia seeds and one of almonds or walnuts every day, and sometimes flax) Beans (black, Lengitls, Kidney, Split peas) and try to get my protein from Yogurt so I didn't eat much saturated fat. (I made sure to eat less than 15 grams of sat fat a day on a 2400 calorie diet)

I would also go out on a morning 3 mile run.

It really *did* help. I'll mention that I wasn't *super extreme* and probably could have done more, I just didn't know *what* more I could do past eating beans/Vegetables/other sources of fiber eating nuts/seeds and avoiding saturated fat.

My ApoB test is in 6 months so I'll know then.

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dynomight's avatar

I'm having trouble understanding the paper that suggests a 90% (for men, 78% for women) decrease in risk. I think that reflects the difference between the highest and lowest "PDAY" scores? I don't quite figure out what that is, but it seems like most people might have intermediate scores, meaning the drop in risk is less?

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